Breast cancer is a significant issue globally. It is the most commonly diagnosed cancer in women. BC accounts for 1 in 4 cases in women globally and contributes to 15% of mortality. As estimated by Global Cancer Observatory (GLOBOCAN) in December 2020, Breast cancer was the most prevalent cancer and the main cause of mortality in Egyptian females. Breast cancer is caused by genetic mutations and DNA damage, both of which are impacted by estrogen exposure. DNA flaws or cancer-causing genes like BRCA1 and BRCA2 may occasionally be inherited. So, having ovarian or breast cancer in the family raises the chance of developing breast cancer. In a healthy person, the immune system targets cells that have aberrant DNA or abnormal development. When this happens to people with breast cancer, tumors develop and spread. Based on which cell origin is involved, breast cancers can be divided into two broad classifications, carcinomas and sarcomas. Carcinomas are breast cancers arising from the epithelial component of the breast, which consists of the cells that line the lobules and terminal ducts. Sarcomas are a much rarer form of breast cancer (<1% of primary breast cancer) arising from myofibroblasts and blood vessel cells.