Background: The understanding of the antibiotic resistance pattern of organisms causing UTI and the etiological profile of UTI is vital for timely diagnosis and adequate management of the disease. Aim: The present study aimed to assess the risk factors and clinical profile of community-acquired urinary tract infections in the Indian scenario. The study also assessed the distribution of bacterial strains in these subjects and the resistance pattern of these microorganisms. Methods: The study included 255 subjects with confirmed community-acquired UTI (CA-UTI) on the positive urine culture were included and assessed for the clinical and microbiological profiles along with the risk factors and symptomatology of the disease. The study also assessed causative microorganisms and their resistance patterns.