Atopic eczema or atopic dermatitis (AD) is the most common type of eczema that causes skin to become itchy, dry, and cracked. The onset of AD is frequently seen in infants and young children, often before the first birthday. Objectives: To determine the combined effect of diet therapy and aerobic exercise on controlling the severity of AD in children. Methods: Sixty children (27 boys and 33 girls) diagnosed with AD participated in this study, aged from 8 to 16 years. The participants recruited in this study randomly assigned, equal numbers in to three groups (A, B and C). Children in the three groups received their ordinary medical treatment prescribed by the dermatologist. Group (A) treated by diet therapy, group (B) treated by diet therapy & aerobic exercise, and group (C) treated by medical treatment only. Before and after 12-weeks of treatment program, the children were examined by the Eczema Area and Severity Index (EASI) for detecting the degree of severity of the eczema and also the Six-Minute Walk Test (6-MWT) was used for detecting their functional capacities. Results: There were statistically significant differences of all outcome measures in each group after treatment (P < 0.05). Similarly, there were statistically significant differences between the three groups in favor of group (A) (P < 0.05). Conclusion: Diet therapy proved more beneficial than diet therapy combined with aerobic exercise on controlling the severity of AD in children.