Oxadiazole and triazole, along with their other derivatives that have been investigated, are members of an important family of compounds that are used in the process of creating new pharmaceuticals. A wide range of pharmacological effects may be attributed to these substances. In recent years, the importance of newly synthesised oxadiazole and triazole derivatives, which have been investigated for their chemical and biological activity, has become increasingly evident. These compounds have been the subject of production and research efforts. In the previous study, it was shown that a synthetic modification of an oxadiazole and triazole ring had a greater efficacy along with enhanced potency and decreased toxicity. This discovery was made possible by the fact that the modification was synthetic. The purpose of this review is to present you with an overview of the research that has been conducted up to this point on oxadiazole and triazole and the biological roles that they serve.