Aim: The aim of the study is to asses the levels of interleukin -11 in pregnant and non-pregnant women with and without chronic periodontitis. Material and Methods: A total of 60 systemically healthy patients aged 18-40 years were included in the study. Subjects were classified into four groups based on probing pocket depth and pregnancy status. Other clinical parameters such as plaque index, gingival bleeding index and oral hygiene index were recorded. Gingival crevicular fluid from these patients was collected using micro-capillary pipettes and the concentrations of IL-11 in the samples were determined using Quantitive ELISA. Results: The levels of Interleukin -11 was highest in pregnant healthy women compared to pregnant chronic periodontitis patient and non pregnant healthy and chronic periodontitis patients Conclusion: The concentration of IL-11 was found to be significantly higher in healthy individuals and pregnant women, as compared to non-pregnant women. Due to its anti-inflammatory properties, IL-11 is believed to have a protective effect against chronic periodontitis, and can therefore be considered a potential biomarker for the assessment of periodontal disease activity.