Introduction: A Comparative study was conducted to determine the effectiveness of Buteyko breathing technique Vs Pranayama (Yoga Breathing) on Pulmonary function, asthma control and Quality of Life of among patient with Bronchial asthma. Design: Quasi experimental research, design was used in this study. Material and Methods: Bronchial asthma patients who fulfills the inclusion criteria, sample size is (n=40) was divided into three groups, assigned to the Experimental group I (Buteyko group n=40), Experimental group II (Pranayama group n=40), Control group n=40. The pre test was conducted for the all three groups, Pulmonary Function test in form of Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 second (FEV1), FVC/FEV1 ratio, Total count, Eosinophil count, IgE and Asthma control and Quality of life of asthma patients also assessed. Then the Experimental group I was taught with Buteyko breathing and Experimental Group II was taught with Pranayama . Control group was given hospital routine treatment for 12 weeks. Post test 1 and post 2 was conducted in 8th week and 12th week. The results were analyzed by parametric and non parametric statistical methods were used. SigmaPlot 14.5 version (Systat Software Inc., San Jose, USA) was used for statistical analysis.