Root canal sealers along with solid core or semi-solid core material aids to fill voids and to seal root canals during obturation and acts for entombment of remaining bacteria and the filling of irregularities in the prepared root canal . Gutta Percha core filling material and root canal sealer . this material alone is not enough to produce and ensure tight seal of the root canal system, it is only adapts to the adjacent dentinal walls. However, root canal sealer is necessary to fill the irregularities and minor discrepancies between gutta percha and canal wall . . A number of herbal products have been tried as root canal sealer for the canal system. . In this Present study Licorice,Guduchi and Bakul were incorporated in a traditional endodontic sealer Endomethasone , and AH Plus to judge their potential of antimicrobial action . The results obtained indicate that the antibacterial effects of herbal solutions are not similar and the difference is attributed to the variation in phytochemical constituents. The major advantages of herbal materials are increased shelf life, costeffectiveness, low toxicity, easy availability and absence of microbial resistance reported.