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ISSN 2063-5346
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“Comparative Evaluation of Basil Seeds powder as superdisintegrant with other disintegrant for formulation of Ketorolac Tromethamine Tablet.”

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Rahul Jadhav, Dr.Prof. Sonia Singh, Pallavi R. Kaple, Vibhavari M.Chatur, Kirti Sahu, Harshada Gaikwad
» doi: 10.48047/ecb/2023.12.si4.1457

Abstract

The purpose of this research was to develop fast disintegrating tablets of Ketorolac Tromethamine containing natural super disintegrant from Ocimum basilicum seed. The mucilage was extracted from seeds of Ocimum basilicum and used to develop the fast disintegrating tablet of Ketorolac Tromethamine. The disintegration property of mucilage powder in FDTs was compared with widely used superdisintegrants like Sodium StarchGlycolate (SSG), and Crosspovidone .The prepared FDTs were evaluated for uniformity of weight, hardness, thickness, friability,anddisintegration time, In-vitro dissolution. From the study, it was concluded that Ketorolac Tromethamine tablet containing Ocimum basilicum seed mucilage powder shows disintegration time 18 sec which was less than SSG and Ac-Di-Sol.

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