Introduction: Present FEM study evaluates and compares the efficiency between stainless-steel and titaniummolybdenum-alloy in terms of canine retraction, canine angulation, canine rotation, stress distribution evaluation of the periodontal-ligament in the mandibular canine region and anchorage loss during canine retraction using 4 different loop designs. Methods: Four replicas of a pre-existing three-dimensional finite element model of the craniofacial skeleton from CBCT data of a patient were used. The 1st premolars were extracted from the left and right sides of the mandibular model and the loops were simulated between the canine and 2nd premolar region and activated. The four loop designs simulated were-T loop, K loop, Snail loop and bulbous helical loop. TMA loops were simulated on the left and SS loops were simulated on the right. The amount of canine retraction, canine angulation, canine rotation, stress distribution at the PDL in the mandibular canine region and anchorage loss were measured in each case. Results: Increased canine displacement, canine rotation and anchorage loss was seen in the SS loops when compared to the TMA loops. Slightly increased stress at the PDL was seen with SS loops when compared to the TMA loops. Maximum tipping was shown by the K loop in TMA wire and minimum tipping was shown by K loop in SS wire, indicating that the stainless-steel loops had better control. Conclusion: The SS loops offer more canine retraction and tipping control whereas the TMA loops provide better rotational control, low anchorage loss and slightly decreased stress at the PDL.