High-quality analgesia after surgery is still a major challenge. A multimodal analgesia approach has been suggested to improve postoperative pain control. Preemptive administration of adjuvant drugs like pregabalin and gabapentin helps in better post operative pain relief, decreases opioid requirement and its side effect. Gabapentin and pregabalin have been used as a part of multimodal analgesia in neuropathic as well as post operative pain. Although pregabalin and gabapentin are effective in treating chronic neuropathic pain, there is limited evidence regarding their effectiveness in post operative pain.