The objective of this study is to reveals that groundwater quality with respect to Physical chemical contamination in a particular winter season and Coliform count is the major tool to determine the bacteriological quality of water. In Salem district, Tamil Nadu, India, both urban and rural areas had their ground water quality assessed using physico-chemical parameters following the North-East monsoon. Water samples were taken throughout Salem district's urban and rural areas. Numerous indices, including pH, EC, TDS, alkalinity, hardness, chloride, sulfate, DO and BOD were investigated in this study. The heavy metal contamination may due to the discharge of industrial, municipal wastes, disposal of solid wastes, land filling and other anthropogenic influences in this region. Groundwater suitability for domestic and irrigation purposes was examined by using WHO and BIS standards. Water quality interpretation was done by using Water quality index, Piper and Wilcox’s diagram. The influence of anions and cations was done by Piper’s trilinear diagram. Groundwater quality for irrigation purpose during winter season is in doubtful category in almost all parts of the study area.