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ISSN 2063-5346
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Comparison of CT and MRI findings in orbital Mucor mycosis in COVID-19 and post COVID-19 patients and correlation with histopathological changes

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Dr Abhilash H D, Dr G Madhavi Latha, Dr Naveen Thirumalashetti, Dr. Pramod B R, Dr. Surya Teja
» doi: 10.53555/ecb/2022.11.12.326

Abstract

Identification of the invasive fungal infection changes in COVID-19 and post COVID-19 patients on CT and MRI can help in making an early diagnosis which will be lifesaving. These imaging changes are proportionate to the fungal invasion into the respective tissue. Materials And Methods: We, hereby evaluated 40 cases of clinically diagnosed orbital Mucor mycosis with concurrent COVID 19 illness at our institute over a period of three months (April 2021 to June 2021). Preoperative CT and MRI findings of each tissue, in every case, is compared with the post operative and histopathology changes. Results: On correlating CT with histopathology, the presence of soft tissue collections and scleral involvement and optic nerve involvement are more accurate in suggesting the presence of fungal invasion. On correlating MRI with histopathology fat stranding, scleral involvement and optic nerve involvement are more accurate in suggesting the presence of fungal invasion. Conclusion: Comparing MR and CT findings with histopathology, statistics revealed that MRI determines the extent of invasion very well, and demonstrates involvement of sclera and optic nerve at an earlier stage. DWI added specificity to the diagnosis by showing restricted diffusion in the path of fungal invasion. Whereas on CT, soft tissue collections earlier demonstrate fungal invasion. But CT is a widely available, fast, effective, and more feasible imaging option specially in sick and uncooperative patients. CT is useful in preoperative planning and in directing the surgical approach.

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