Introduction: The popularisation of self-ligating brackets in Orthodontics over the years has led to increase in queries whether they would have an effect on Early Apical Root Resorption (EARR) different from the conventional brackets. Therefore, a critical systematic review and meta-analysis would be favourable at this stage to understand the advantages, drawbacks and effects of self-ligating and conventional brackets on EARR during Orthodontic treatment. Materials and methods: A substantial amount of manual and electronic search was performed via databases such as PubMed, EMBASE and Cochrane library until June, 2022. The participants of the recruited studies received Fixed Orthodontic treatment wherein comparisons were made between Self-ligating and Conventional brackets. The data extraction and evaluation of risk of bias was done. The outcomes underwent statistical pooling by using Review Manager 5.4. Results: Seven studies were included in this systematic review and meta-analysis. Less EARR was seen in self-ligating group for maxillary central incisor. For maxillary lateral incisor, not much difference in the values was noticed. For mandibular central incisor, majority of the studies showed no significant difference in the values and for mandibular lateral incisor the EARR value showed no notable variation for both the groups. Conclusions: On the basis of the data and literature gathered it can be well recognised that Self-ligating brackets stand to be superior than conventional brackets in multiple qualities.