The adoption of health information technology (HIT) in nursing and drug practice should be given priority because, in the present world of healthcare, saving patient lives is a rigorous health system demand. This in-depth analysis is conducted through a critical analysis of current literature, which reveals the precise impact that the growing adoption of HIT exerts on these reviewed signposts. Along with the conclusion that outlines separate opportunities afforded by HIT and consequent barriers, the review conducts in-depth exams of the gathered information via graphics and figure representation. The process of assessing the gaps highlights those areas that have been inadequately studied, hence, more research is still necessary. Building upon the assessment, the report introduces valuable suggestions for upcoming research and practice-related applications to improve the precision and effectiveness of HIT integration in nursing and pharmacy franchises. Although our discussion broadly represents the existing status of the matter, this review is still expected to be beneficial source material for the stakeholders who are aiming to facilitate health care delivery by taking advantage of HIT tools, as it provides a balanced consideration of HIT's impact on workflow effectiveness and patient safety and also maps out the way forward for those seeking future developments in the field.