Palliative procedures allow palliative care workers to play a significant role in improving the quality of life of cancer patients who are under radiation therapy. This exhaustive survey discusses the different therapeutic interventions of palliative care used in managing cancer patients treated with radiation therapy. Crucial interventions are explored, encompassing pain sensation management, symptom control, psychosocial assistance, and end-of-life care options. This review illuminates results from clinical research, experimental trials, and specific cases to evaluate the effectiveness and influence of those approaches on healthcare outcomes. Furthermore, practical guidelines for incorporating palliative care treatments into radiation therapy protocols are given to maximize patient-centered care and increase overall treatment efficacy.