The significance of blood in sustaining and supporting human bodily functions cannot be understated. It is crucial for various medical procedures, particularly during surgeries, and a scarcity of blood supply poses significant challenges. In response to this global issue, the development of synthetic red blood cells (RBCs) using nano-technology has emerged as a promising solution. These artificial blood substitutes can serve as a viable alternative to human RBCs, addressing the shortage of blood for transfusions. The primary function of synthetic RBCs is to facilitate oxygen transport, mirroring the actions of their human counterparts, including clotting capabilities and pathogen responsiveness. This paper provides an overview of the recent advancements in the field of synthetic RBCs, highlighting their potential as a vital component in addressing the shortage of blood supply. The work done & presented in this paper is the result of the final year one year project work that has been done by the final year engineering students of the college and as such there is little novelty in it and the references are being taken from various sources from the internet, the paper is being written by the students to test their writing skills in the final stages of their engineering career and also to test the presentation skills during their final year project presentation and the work done & presented in this paper is the report of the undergraduate project work done by the students.