Within the context of the healthcare system, clinical laboratories are of critical importance. Clinical laboratories provide objective medical data that supports about sixty to seventy percent of clinical choices. However, the evidence that supports this claim is poorly documented, and laboratories continue to lack visibility, despite the undeniable impact that they have on patient care and public health. We place a strong emphasis on the necessity of establishing a harmonized and coordinated national public health laboratory system, particularly for the purpose of conducting an outbreak investigation. This system should incorporate various categories of public health laboratories within a country and should be closely connected to the national public health delivery system as well as regional and international high-end laboratories.