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ISSN 2063-5346
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CORRELATION BETWEEN MODEL FOR END STAGE LIVER DISEASE (MELD) SCORE AND URINARY SODIUM - POTASSIUM RATIO IN PREDICTING HEPATORENAL SYNDROME IN CIRRHOTIC PATIENTS, TERTIARY CARE HOSPITAL, EAST GODAVARI.

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Dr. Chakravarthy D J K, Dr. Sree Padma Challa, Dr. Divya Mahalakshmi Cholan, Dr. Kovvuri Hari Lalith Reddy, Dr. Ganapathi Swamy Chintada, Dr. S V Ramanamurty
» doi: 10.48047/ecb/2022.12.10.566

Abstract

Cirrhosis, being a late stage progressive hepatic fibrosis, is characterized by the distortion of architecture and formation of regenerative nodules [1].The natural history of the disease is characterized by an asymptomatic compensated phase followed by a decompensated phase marked by development of overt clinical signs, the most frequent being ascites, bleeding, encephalopathy, and jaundice [2]. Hepatorenal syndrome is a common cause of renal failure in cirrhosis and is characterized by functional renal vasoconstriction leading to severe reduction in GFR with minimal renal histologic abnormalities [3,4,5,6,]. Recently introduced therapies have demonstrated efficacy in the prevention and management of Hepatorenal syndrome. Therefore, it is important to identify the patients who are at risk of developing Hepatorenal syndrome early at the time of admission. This study focuses on identifying Hepatorenal syndrome using limited available resources which includes the MELD score which is objective, reproducible, and readily available in all settings. Random urinary sodium-potassium ratio can replace 24-hour collection for sodium excretion in daily clinical practice

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