Background: Neonatal Jaundice (NNJ) is a common disorder worldwide and one of the important contributors to high neonatal morbidity and mortality. Cord Blood Bilirubin samples are easy to collect for estimation of bilirubin levels of new-born at birth. It helps in detecting new-borns who are at a low risk of developing hyperbilirubinemia and minimizes unnecessary prolongation of hospitalization or hospital readmission for hyperbilirubinemia Material and methods: The study was a prospective observational study conducted in a tertiary care hospital of North India. The sample size was 110 healthy full term new-borns. Cord blood bilirubin (CBB) was estimated at birth. This was followed by clinical examination of all new-borns daily for jaundice and its severity assessed by Kramer’s score. Total serum bilirubin(TSB) values was also estimated at 72 hours of age.