We focus on the corrosion behavior of Al-2014 alloy in the 1M HCl acidic medium. Also, the inhibition property of Amoxicillin on Al-2014 alloy was studied with different concentrations at different temperatures. The surface analyses through micrographs were analyzed for the inhibitor-treated and untreated Al-2014 surface by FE-SEM measurement. It reveals that the Amoxicillin-treated surface has prevented corrosion compared to the untreated Al-2014 alloy. The potentiodynamic measurements reveal that the Al-2014 alloy with 150ppm of inhibitor solution has the highest tendency to prevent corrosion in 1M HCl solution at different temperatures. The inhibition efficiency is found to be 43% at 25˚C and 40% at 35˚C. The inhibition efficiency was also verified from the adsorption isotherm, the high inhibition rate is due to the value of ‘Kads’ ((6592.3kJ/mole (25˚C), 4524.09kJ/mole (35˚C)) and ΔG˚ ≈ -33.8 (25˚C), -33.9 (35˚C) kJ/mole. From the EIS studies, the inhibition samples show a higher ‘Rct’ value implies good corrosion resistance. It is also confirmed from the equivalent circuit by Nyquist plots.