The COVID-19 pandemic, which emerged at the end of 2019 in China, quickly spread around the world in early 2020, with devastating consequences for the global economy and human health. The pandemic has left more than one million people dead and several million others in various states of morbidity. A 2022 World Bank report claims that the COVID-19 pandemic sent shock waves through the global economy, triggering the largest economic crisis in more than a century. The COVID-19 pandemic unleashed a health and economic emergency in Sub-Saharan Africa. It also triggered a dramatic impact on local economies across the region, prompting a sharp decline on GDP growth to 1.9% in 2020, the poorest economic outcome in more than three decades (IMF, 2021). While women comprise 50% of Africa’s population, they account for only 33% of its collective GDP. Empirical studies reveal that at the current rate of progress, gender parity across the region may take more than 100 years to be achieved (McKinsey Global Institute, 2019). In a paradox of gender inequality, Africa has witnessed rising cases of domestic violence against women and girls since lockdowns emerged in March, 2020. Cases of rape in Nigeria and South Africa, as well as child molestation and sexual trafficking in Kenya assumed epidemic dimensions. Women and girls also showed a disproportionate burden associated with the COVID-19 pandemic in access to education, employment, gender-based violence, as well as palliatives distributed by governments to mitigate the virus. The trends were discernible in Angola, Ethiopia, Kenya, Nigeria, as well as most other countries across Sub-Saharan Africa.