Menopause/ Rajonivritti is a normal physiological phenomenon in women’s life due to the aging process. During this period, they are often affected with various Manasa Bhavas which ultimately leads to somatic and psychological disturbances. Being a common and distressing problem, it needs effective and safe treatment. Ayurveda recommends various solutions for a safe and happy transition into menopause. Timely intervention with appropriate Panchakarma therapies can pave an effective way to tackle the symptoms associated with menopause. The management mainly focuses on strengthening and rejuvenating the reproductive system and whole body. After analysing the samprapti and the lakshanas manifested, vata pitha hara chikitsa is to be adopted here along with Srotosodhana and Rasayana chikitsa. Panchakarma therapies in form of Antahparimarjana and Bahiparimarjana chikitsa can be employed for controlling the psychological manifestations of Rajonivritti. The Antahparimarjana chikitsa includes Snehapana, Virechana, Nasya, Niruha basti and Matra basti. Bahiparimarjana chikitsa includes Abhyanga, Pada abhyanga and Murdhni thailas.