The present study is aimed to reveal the ancient texts and find a group of drugs (Anjandi gana) for treatment of Pittaja vyadhi like coagulopathies, burning sensation and poisoning. Materials and method: A systematic and comprehensive literature search was conducted on Ayurvedic classics to explore the rationale behind the traditional uses of Anjandi gana. In order to enhance clarity and scientific accuracy, the Ayurvedic Pharmacopoeia and other relevant scientific works were also consulted. Additionally, international and national journals, as well as other published materials, were searched to provide scientific evidence for the uses of Anjanadi gana. This research aims to intrigue scholars who are interested in Anjanadi gana. Discussion: Anjanadi gana dravya are hepatoprotective, anti-allergic, radio-protective, haemostatic, anti-hemorrhoidal, anti-microbial, anti-inflammatory, neuro-protective and anti diabetic activity. Conclusion: The present review article throws ancient luminosity behind the therapeutic uses of Anjandi Gana of Ashtanga Hridaya. Drugs of Anjanadi gana are mostly aromatic and helpful in function of liver detoxification, so that poisonous drugs may be easily detoxified and may be useful in cumulative poisoning of pesticides and diseases due to incompatible diet