Culture is a salient feature in every social setup with a rather latent but unwavering effect on social and even professional dynamics. Similarly, nurses’ level of cultural competency can impact the quality of patient care services. With the heightening influx of internationally qualified and expatriate nurses into Saudi, concerns continue to grow regarding the quality of nurse-patient therapeutic relationships. This narrative review explores the cultural competency among nurses working in Saudi Arabia, factors affecting their cultural competency, and relevant improvement measures. Accordingly, empirical studies reported reliably good levels of cultural competency among the nurses in Saudi Arabia, local, and expatriate. However, literature evidence also showed that the level of cultural competency among nurses varies with demographic features, such as age, gender, nationality, and other specific factors, like education level, training, language competency, and leadership. Measures, such as regular training, embedding cultural sensitivity into the nursing curriculum, and providing additional resources, such as language translators can improve nurses’ cultural competency. Nevertheless, higher levels of evidence are missing regarding the development and testing of interventions to improve cultural competency among nurses working in Saudi Arabia.