A breakthrough in cross-coupling chemistry, the copper-catalyzed Ulmann reaction provides a reliable and effective way to obtain biaryl compounds, which are essential for the synthesis of complex molecules with a wide range of uses. The Ulmann reaction, which is catalyzed by copper and is a fundamental mechanism in modern organic synthesis, offers scientists a sustainable and efficient method of obtaining biaryl compounds, a family of compounds that are essential to materials science, agrochemicals, and pharmaceuticals. The goal of this study of the literature is to provide insight into how chemical reactions evolve during organic synthesis.