The comprehension of atomic structures and the interactions between atoms is crucial for a thorough understanding of chemistry. This paper explores the application of game theory concepts to elucidate the reactions occurring between elements in the periodic table. The study's results indicate that coordination, anti-coordination, cooperation, and non-cooperation among atoms and molecules play a significant role in the formation of chemical bonds, as predicted by game theory. Moreover, the predictability of chemical reactions and their resulting chemical behavior and physical properties can be inferred. Several illustrative examples of various chemical reactions are provided to validate the practicality of these assertions