Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
HIV, which causes AIDS, is one of the deadliest diseases and the sixth leading cause of death. The reported poor bioavailability of non-nucleoside reverse transcriptase inhibitors used to treat HIV infection is related to first pass metabolism, protein binding and enzyme metabolism. They are also less permeable to the blood-brain barrier. The central nervous system is considered the most important HIV reservoir