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ISSN 2063-5346
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BIOCHEMISTRY OF FASTING – A REVIEW ON METABOLIC SWITCH AND AUTOPHAGY.
Volume - 13 | Issue-1
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ONE-POT ENVIRONMENT FRIENDLY SYNTHESIS OF IMINE DERIVATIVE OF FURFURAL AND ASSESSMENT OF ITS ANTIOXIDANT AND ANTIBACTERIAL POTENTIAL
Volume - 13 | Issue-1
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MODELING AND ANALYSIS OF MEDIA INFLUENCE OF INFORMATION DIFFUSION ON THE SPREAD OF CORONA VIRUS PANDEMIC DISEASE (COVID-19)
Volume - 13 | Issue-1
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INCIDENCE OF HISTOPATHOLOGICAL FINDINGS IN APPENDECTOMY SPECIMENS IN A TERTIARY CARE HOSPITAL IN TWO-YEAR TIME
Volume - 13 | Issue-1
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SEVERITY OF URINARY TRACT INFECTION SYMPTOMS AND THE ANTIBIOTIC RESISTANCE IN A TERTIARY CARE CENTRE IN PAKISTAN
Volume - 13 | Issue-1
DESIGN, FORMULATION AND EVALUATION OF ORAL FAST DISSOLVING FILMS OF ANTI-HYPERTENSIVE DRUG
Main Article Content
Abstract
The objective of present study was to develop fast dissolving oral films of Anti-Hypertensive drug Ranolazine using solvent casting technique. A response surface methodology experimental design was applied for the optimization of fast dissolving film using BoxBehnken experimental design. The concentration of X1 (mango kernel, 100–400 mg), X2 (MDX 0–100 mg), and X3 (PG, 15–30%) were preferred as independent factors. Y1 (Tensile Strength; MPa), Y2 (Disintegration Time; Sec), Y3 (Folding Endurance; Folds), Y4 (Elongation; %), and Y5 (% drug release; min) were considered as dependent variables.
Article Details
