Arsenic (As) contamination of groundwater affects the health of about 140 million people in India. Long-term exposure to As increases mortality dramatically because it causes a variety of malignancies, lung diseases, and cardiac problems. The current study used a method that enables the measurement of the concentration of heavy metals and arsenic in various water samples from various regions of West Bengal districts. Howrah, South 24 Parganas, North 24 Parganas, and Kolkata were the chosen districts. The arsenic pollution, as well as the contamination of Cd, CN, Pb, Hg, Ni, Mo, Cr, Total suspended solid, Total hardness (CaCO3), and BOD and COD levels, were all tested. The concentration in water containing arsenic samples varied from 0.22 to 1.92 mg/L, above the allowable level of arsenic, which is 0.01 mg/L in drinking water (according to WHO). According to our research, chronic poisoning from arsenic accounts for the majority of water pollution and poses a risk to the 3.5 million people and communities who use this untreated water.