Currently, many modern medical specialists are using folk medicine methods in the treatment of various diseases. The conditions created today serve as a great ground for the cooperation of modern medical workers and folk medicine specialists. If the modern doctor and healer work together, it will be possible to prevent and treat many diseases that are bothering humanity today. We have analyzed the scientific literature, taking into account the importance of water-soluble vitamins, flavonoids and steroids in the diagnosis and treatment of kidney stone diseases. During the research, we have found that watermelon seeds are perfect in every way. In order to apply the results of this scientific research to a practical approach, we conducted practical experiments with watermelon seeds of the "Shirin" variety grown in Uzbekistan and China. The main goal of choosing watermelons grown in China is that China is the main producer and exporter of watermelons in the world.