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ISSN 2063-5346
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DEVELOPMENT AND CHARACTERIZATION FUROSEMIDE LOADED MUCOADHESIVE MICROSPHERE

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Vikas Sharma1* , Jiyaul Hak2 , Dr. Mojahid ul Islam, Dr. Prabhakar Vishvakarma4
» doi: 10.48047/ecb/2023.12.si5a.0449

Abstract

Solid dispersion can be defined as a dispersion in which drug eutectic mixes are formed with watersoluble carriers by melting of their physical mixtures. The term "solid dispersion" refers to an inert carrier and matrix containing one or more active ingredients that have been dispersed in a solid form using a melt, fusion, solvent, or melts solvent preparation process. The drug's permeability and oral bioavailability are significantly influenced by its solubility. Some medications' solubility makes it difficult for their formulation to be acceptable for oral administration. The hydrophobic medication and the hydrophilic matrix are used to create the solid products, which are made up of at least two distinct components. The dispersion matrix may have either an amorphous or crystalline shape. The medication may then be dissolved, either in crystalline or amorphous form[1-5]

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