The rapid beginning of action, high blood level, avoidance of the first-pass effect, and exposure of the medication to the gastrointestinal tract have lately sparked interest in transmucosal drug delivery (TMD) systems using mucoadhesive polymer. In the presence of chitosan, a brand-new mucoadhesive polymer complex for the TMD system was created using hydroxyl propyl methyl cellulose (HPMC) and chitosan. The film made of the chitosan/HPMC polymer complex contained triamcinolone acetonide (TAA). Without interacting with the polymer complex, TAA was uniformly distributed throughout the chitosan/HPMC polymer complex film. Time, pH, drug loading quantity, and the ratio of chitosan to HPMC all influenced the release behaviour of TAA from the mucoadhesive polymer film. TAA may be released from the chitosan/HPMC polymer complex film, according to the examination of the drug release from the mucoadhesive film