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ISSN 2063-5346
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DEVELOPMENT, CHARACTERIZATION, AND EVALUATION OF ROSA ALBA L EXTRACT-LOADED PHYTOSOMES

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Suraj Mandal, Darla Raju, Priyanka Namdeo, Akhilesh Patel, Amit Kumar Bhatt, Jeetendra Kumar Gupta, Mohd Haneef, Prabhakar Vishvakarma, Umesh Kumar Sharma
» doi: 10.31838/ecb/2023.12.1.042

Abstract

In today's modern world, medicinal plants and the phytochemicals they contain are an excellent choice of treatment for a wide variety of illnesses. However, because of their low selectivity and bioavailability, their clinical applicability may be severely limited. As a consequence of this, the phytosome technology that was developed by Indian researchers is a cutting-edge strategy that was developed in an effort to address the issue of low bioavailability. The term "phyto" is used to refer to plants, and "some" is used to refer to individual cells. This cutting-edge formulation combines a standardised plant extract with phospholipids in order to produce lipid-compatible molecular complexes with enhanced absorption and bioavailability. Both the phosphatidyl moiety, which serves as the head of the bifunctional compound and is naturally lipophilic, and the choline moiety, which serves as the tail of the bifunctional compound and is naturally hydrophilic, are examples of chemical compounds. The hydrophilic phytoconstituents are bound to the choline portion of the phosphatidylcholine molecule, and the phosphatidyl part of the phosphatidylcholine molecule, which is lipid-soluble, then envelops the choline-bound complex.

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