Floating pulsatile drug delivery systems are gaining popularity because they administer medications in the appropriate place, at the right time, and in the right amount. The floating pulsatile idea is used to improve the stomach residence of a dosage form with a lag phase followed by a burst release. In recent years, numerous methods for chronopharmaceutical drug delivery have been created and thoroughly investigated, including time-controlled, pulsed, trigged, and programmed drug delivery systems. The current review paper focuses on chronotherapy disorders that require chronotherapeutics, pulsatile drug delivery, particularly floating pulsatile drug delivery, and new advancements in this technology.