While hypertension and diabetes are significant killers in Mexico, therapy for these conditions is complicated by factors like food, physical exercise, drug treatment adherence, etc., all of which depend heavily on the patient's actions. Fifty-one patients with hypertension, diabetes, or both participated in a quasi-experimental study examining the impact of cognitive behavioral intervention on these and other elements of illness treatment. Individualized interventions focus on patients' psychological factors that compromise their health and compliance with treatment. Life satisfaction, resiliency, depression, anxiety, blood sugar, blood pressure, and hypotensive medication dosage were all evaluated before and after treatment.