Background: A number of acute and chronic illnesses are at risk due to excess body weight (EBW). On the other hand, the "obesity paradox" contends that larger body weight may protect against some illness outcomes. Objective: The impact of EBW on the incidence and course of the pancreatitis and the pancreatic cancer (PC) is discussed in this article. The use of several EBW assessment techniques makes it difficult to compare results. However, EBW, particularly the visceral obesity, is separate risk factor and the predictor of the poor outcome in the acute pancreatitis (AP) and the PC. Results: Findings suggesting a protective effect are probably the result of not taking fat distribution or other variables into account. Few research on chronic pancreatitis (CP) suggest that increased body mass is associated with a lower incidence and better prognosis. To prove the existence of an obesity paradox, however, there is not enough supporting data. It is yet unclear exactly how EBW influences the disease continuum, although both general and disease-specific effects appear to be at play. Conclusion: In AP and PC, EBW is linked to a higher incidence and a bad result. Less proof exists for the CP connection. Therefore, it is advised to maintain a healthy weight throughout the course of the condition.