Objectives: To evaluate the effect of aerobic exercises on controlling and decreasing weight gain postthyroidectomy. Design: A double-blinded randomized, controlled study. Setting: Outpatient setting. Subjects: The study included fifty - six female thyroidectomy patients. They were between the ages of 30 and 45 years. After 9-12 months had passed since the total thyroidectomy, the patient began treatment. They were divided into two groups of equal numbers and chosen from the outpatient clinic at Cairo University's Department of Physical Therapy (28 patients for each group). Group (A) received aerobic exercises (Treadmill and Rope-skipping exercise) as well as medical treatment. Group (B) received their medical treatment only. Intervention: 8 weeks with 5 weekly sessions, the treadmill time is for 45 minutes and the rope skipping exercise for 30 minutes. Outcome measures: the body mass index (BMI) and the waist-to-hip ratio (W HR) were measured before and after eight weeks of interventions. Results: When comparing the study group to the control group, there were statistically significant differences in the groups' mean body weight, body mass index, and weight-to-height ratio (p < 0.001). After eight weeks of intervention, the mean (SD) for weight, BMI, and W/H ratio was 68.42 ± 3.32 kg, 25.26 ± 0.45 kg/m2 , and 0.83 ± 0.02 in the study group, and 71.66 ± 3.02 kg, 26.64 ± 0.5 kg /m2 , and 0.86 ± 0.03 in the control group, respectively. Conclusion: Adding Aerobic exercises to the medical treatment might be more effective in decreasing and controlling weight, BMI, and waist-to-hip ratio post-thyroidectomy