Patients with chronic kidney disease (CKD) continue to have poor management of mineral abnormalities in spite of multiple therapies. Mineral and bone abnormalities associated with Mineral & Bone Disorder (MBD) are a significant source of morbidity and death. The goal of the present study is that examine how the impact of measuring parameters effects on mortality and morbidity in chronic dialysis patients are affected by mineral and bone diseases (MBD) and their components. Materials and Methods: The study was conducted on Bundelkhand region in MLB Medical College, Jhansi on 170 cases of all adult age group suffering from CKD. Their parameters were detected by evaluating the bone biomarkers. Observation & Results: It was observed that the cases in stage IV having 32 cases and 18.32% followed by stage V which have 138 and 81.17%. The Mean ± SD in biomarkers of Ca, P, Vit-D and iPTH were found that 3.09 ± 1.68 followed by 9.7 ± 0.14, 10.48 ± 2.51 & 175.5 ± 14.84 respectively. The mortality rate were also calculate that 2 (6.25%) and 9 (6.52%) in both the stages. Conclusion: This study revealed that it is vey useful tool for the management of CKD-MBD which helps in the knowing about the diagnosis and its pathophysiology for future clinical correlation