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ISSN 2063-5346
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EFFECT OF EMPAGLIFLOZIN VS PIOGLITAZONE VS METFORMIN WITH URSODEOXYCHOLIC ACID AND VITAMIN E IN NON-ALCOHOLIC FATTY LIVER DISEASE AND NON-ALCOHOLIC STEATOHEPATITIS IN EGYPTIAN PATIENTS WITHOUT DM

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Ahmed Dorrah1 , Sayed Farouk1 , Wael Safwat2 , Omar Sabry3 , Khaled Mabrouk3 , Mohammed Kamal Dewidar2*
» doi: 10.48047/ecb/2023.12.Si8.672

Abstract

Background: Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most common cause of chronic liver disease and is now among the top causes of cirrhosis, hepatocellular carcinoma (HCC). No pharmacotherapies are approved for NAFLD in non-diabetic patients. Aim: We aimed to compare empagliflozin to pioglitazone and a combination of metformin, Ursodeoxycholic acid, and vitamin E (MET+UDCA+VitE) in nondiabetic patients with NAFLD, and to assess the impact of these therapies on autotaxin and cytokeratin 18.

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