Peri-implantitis involves inflammatory changes affecting the soft tissues surrounding the implant resulting in loss of the supporting bone surrounding the implant. Thus the present case report aimed to describe the surgical treatment of peri-implantitis, with a regenerative approach along with low level laser therapy (LLLT) as an adjunctive. Case Presentation: A 24 years female patient reported with falling off crown from implant placed in 16 region. Radiographic assessment reveled there was vertical bone loss around the implant. So, bone graft with membrane along with LLLT was done to sustain the implant. After 3 months there was uneventful healing and adequate bone fill was seen radiographically. Conclusion: It was concluded that after treatment it showed good clinical result for the long-term sustainability of the implant.