The concept of accelerated tooth movement has been receiving constant attention. (1) Micro-osteoperforation (MOP) is one of the least invasive and effective surgical techniques described for use in conjunction with orthodontic treatment. Aim - To evaluate the effect of micro-osteoperforation on rate of canine retraction in patients undergoing orthodontic treatment.All published full text RCTs since 10 years on PubMed database was used. Results - Total 8 RCTs were screened which involved micro-osteoperforation before canine retraction. Among 8 RCTs, 5 conclude that MOP increases the rate of canine retraction and 3 concluded that there was minimal or no difference on rate of canine retraction. Conclusion - Micro-osteoperforationis a minimally invasive technique with little patient discomfort also it eliminates the disadvantages of other surgical procedures. Thus, Micro- osteoperforation using Regional Acceleratory Phenomenon (RAP) shortens the duration of adult orthodontic treatment providing efficient outcome.