Background: Elderly women with cervical cancer experience many physical and psychological symptoms due to disease itself and its treatment modalities. So, provision of palliative care intervention to these patients can relief these symptoms and improve their quality of life. Aim: This study aimed to evaluate the effect of palliative care on quality of life for elderly women with cervical cancer. Methods & Materials: A quasi- experimental design was used in this study and applied on 60 elderly women who suffered from cervical cancer, purposively assigned according to study inclusion criteria, conducted at outpatients’ gynecological oncology at outpatient clinic at Zagazig University Hospitals. Tools: Three tools were used for data collection: A structured interview questionnaire, Functional Assessment of Chronic Illness Therapy Palliative Care (FACIT- Pal questionnaire) and the MD Anderson Symptom Inventory- Korean (MDASI-K). Results: The study findings reveal highly statistically significant improvement in all domains of quality of life and in total quality mean score in post intervention than pre intervention. Where, the total mean was improved from 57.75 ± 4.99 pre intervention to 101.65 ± 4.28 post intervention. There was statistically significant relation between total quality of life of studied elderly women and marital status post the program. Also, the current study result reveals that, educational level had a statistically significant negative correlation with symptoms requiring palliative, and palliative care quality of life had a highly statistically significant negative correlation with symptoms requiring palliative. Conclusion: There was significant improvement in all domains of quality of life of studied elderly women with cervical cancer due to efficacy of palliative care intervention.