Maize is an important cereal crop cultivated worldwide. However, the temperature extremes are threatening the yield sustainability of maize. Maize plants are sensitive to drought stress and there is a strong decline in grain yield as plants face drought stress above the threshold level for a prolonged duration. The various biochemical and physiological parameters gets altered due to the drought stress. Higher activities of antioxidant enzymes under abiotic stress condition might be useful for the seedlings to cope up with oxidative damage by heat stress. The exogenous application of phytohormones enhanced the activities of antioxidant enzymes such as catalase, peroxidase and superoxide dismutase. The present study was conducted at the control condition (ambient) and in the drought stress condition (exposing drought at 45 DAS) to evaluate the influence of phytohormones on the enzyme activities such as catalase, peroxidase and superoxide dismutase. These studies were carried out in the maize seeds COH(M) 8 for identifying the suitable phytohormone for the drought stress mitigation.