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ISSN 2063-5346
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Effect of Quercetin loaded Chitosan Nanoparticles and 5-Fluorouracil loaded Chitosan nanoparticles on Tongue Squamous Cell Carcinoma Cell Line

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Mohammed Sheikh Mohammed1 , Adel Mohamed Ragheb2 , Eman Sobhy ElShamy3 , Eman Mohy El deen Megahed
» doi: 10.48047/ecb/2023.12.si8.491

Abstract

Background: Anticancer medications often have a limited therapeutic index, multiple drug resistance (MDR), and severe side effects. As a result, novel therapeutic techniques have been examined, and the most promising one is naturally obtained substances with known anticarcinogenic activities. Aim: To assess the effect of quercetin-loaded chitosan nanoparticles (Qu-ChNPs), 5-fluorouracil-loaded chitosan nanoparticles (5-FU-ChNPs) and dual quercetin and 5-fluorouracil-loaded chitosan nanoparticles (Qu and (5-FU)- ChNPs) on tongue squamous cell carcinoma (TSCC) cell line

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