Background: Diabetic patients frequently experience diabetic neuropathic pain(DPN) which has a relatively high incidence rate worldwide. The prevalence of developing neuropathic symptoms in type II diabetics is 40.3%. Drugs and exercise therapy are currently the most prevalent forms of treatment for DPN. As drug therapy has its side effects, as per the researchers and various studies, the role of exercise therapy has been proven more beneficial. Objective: The aim of this study was to compare the effects of structured exercise protocol to the conventional physiotherapeutic protocol. The aim of structured protocol is to focus moderately on exercise for lower extremities and mildly on upper extremities which are doable as well as challenging for the patients that not only reduce pain but enhance functionality. Methodology: 99 subjects experiencing neuropathic pain symptoms associated with Type II diabetes for more than 10 years were randomly assigned into experimental and control group out of which there were 12 dropouts during the study intervention. LANSS questionnaire was given to the subject pre and post intervention to measure the difference in the intensity of pain. Result: 87 patients were filled the pre and post test forms which resulted, in the pre-test LANSS score of ≥12 was scored by 38 subjects from control group(n=49) and 39 subjects from experimental group(n=50), whereas after the intervention in the post-test LANSS score of ≥12 was scored by 35 subjects from control group(n=40) (p=0.3058) and 18 subjects from experimental group(n=47)(p=<0.0001). Conclusion: Exercises performed with no need of special equipment and also that can be easily carried at home helps to reduce neuropathic pain symptoms resulting in immediate and long lasting effects of exercise therapy.