Introduction: The morphological anomalies in the lower leg, referred as the diabetic foot, are among the most common as well as potentially fatal consequences of diabetes mellitus. The enzymes in Carica papaya are very useful for debriding ulcers and wounds. There are over 13 million people in the world who were diagnosed with diabetes; 15% of those people will develop a diabetic foot ulcer at some point in their lives; 30% to 50% of those people will need to have other foot amputated within 5 years; and also, numerous studies have revealed that papaya dressing is useful among diabetic foot ulcer patients