Non-pharmacological interventions are providing promising evidence in reducing late-life depression and related issues. Particularly, recent studies show evidences that Heartfulness meditation has been helping older adults to improve their late-life problems. Objective: The aim of this study is to examine the effectiveness of Heartfulness meditation in institutionalized older adults who have problems with late-life stress, anxiety and depression. Also, this study aimed to examine the effect of Heartfulness meditation intervention in improving the quality of life of older adults.