Morphine is one of the most potent opioid analgesics recommended by World Health Organization (WHO) but long-term usage can lead to addiction. Morphine is a phenolic chemical and an alkaloid originating from the poppy plant that induces central nervous system dysfunction and is poisonous in high doses so, it must be properly controlled and kept within safe ranges. Several analytical techniques such as thin layer chromatography, gas chromatography, and high-performance liquid chromatography have been employed, however these approaches are expensive and time consuming. Electrochemical sensors, in comparison, are efficient analytical devices because of their desirable qualities, such as minimal cost, portability, high sensitivity, and ease of operation for on-the-spot or mobile detection of morphine, which is electroactive in nature. Cyclic and differential pulse voltammetry modes have been explored. A screen-printed carbon electrode has been functionalised by gold nanoparticles which considerably increases the sensitivity of the sensing platform as they have huge surface area relative to their volume. Its further conjugated with antibodies for precise antibody-antigen recognition of morphine thus increasing the selectivity of the sensing platform.