Background: Massive subarachnoid hemorrhage (SAH) or thromboembolic events caused by the dislodgement of intraluminal thrombus inside the aneurysms fundus may make giant intracranial aneurysms clinically obvious. These conditions manifest as increasing localized neurologic impairment. Endovascular treatment of these aneurysms was the focus of this study, which aimed to assess its safety and effectiveness. Methods: This prospective research was conducted on 16 patients diagnosed with large and giant intracranial aneurysms, from 2019 to 2022 underwent 20 endovascular therapeutic procedures. Results: 16 patients (9 females and 7 males) with large and giant intracranial aneurysms. Six aneurysms were ruptured (37.5%) and ten aneurysms were unruptured (62.5%). Age ranged from 2 years old to 60 years old. As regard clinical outcome 19 procedures with favorable (95%) and unfavorable in one procedure (5%). Regarding grades of aneurysm occlusion in the final control angiography, it was grade 0 in 5(25.0%) patients, grade 1in 11(55.0%) patients, grade 2 in 2(10.0%) patients, grade 3 in 2(10.0%). There is a significant difference was found between aneurysm morphology and the grade of aneurysm occlusion (p= 0.041). The aneurysm regrowth in relation to the grade of aneurysm occlusion is nearly significant and this indicated that if a big number of cases was studied it may become significant (P=0.090). Conclusions: Endovascular management of large and giant intracranial aneurysms is feasible with high efficacy and more safety profile.