Oral dispersible tablets (ODTs) have gained significant attention in the pharmaceutical industry as a unique dosage form that quickly disintegrates or dissolves in the mouth without requiring water. Their popularity has surged due to advantages such as improved patient compliance, easy administration, precise dosing, and pain avoidance. ODTs are especially beneficial for individuals with dysphagia, who have struggled to swallow oral tablets. This review explores several patented technologies, including Zydis, OraSolv, DuraSolv, Wowtab, Flashdose, and Flashtab, which use different mechanisms to achieve fast-dissolving properties while ensuring stability and taste masking. ODTs offer great potential in enhancing drug safety and efficacy, particularly for patients with physical or physiological limitations, children, geriatric individuals, and travellers. They provide a promising solution for non-invasive drug delivery and improved patient acceptance and compliance. However, the review also acknowledges challenges in ODT formulation and the need for advanced technologies to overcome these hurdles. Despite the challenges, the growing demand for ODTs in the pharmaceutical market is expected due to their rapid action, convenience, and patient-friendly characteristics. With ongoing advancements and increased patient demand, ODTs are likely to become a preferred choice in drug delivery systems.